Abstract | PURPOSE: MATERIALS AND METHODS: RESULTS: CONCLUSIONS: Our results suggest that severe hepatic dysfunction does not significantly alter the serum concentration of PSA. These data, combined with recent investigations demonstrating an intrahepatic mechanism for PSA elimination, suggest that the liver has a significant reserve to metabolize the relatively small quantities of PSA in the circulation.
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Authors | P B Williams, J A Eastham, D J Culkin, J A Mata, D D Venable, O Sartor |
Journal | The Journal of urology
(J Urol)
Vol. 158
Issue 5
Pg. 1867-9
(Nov 1997)
ISSN: 0022-5347 [Print] United States |
PMID | 9334619
(Publication Type: Journal Article)
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Chemical References |
- Prostate-Specific Antigen
|
Topics |
- Adult
- Aged
- Humans
- Liver
(metabolism)
- Liver Failure
(metabolism, surgery)
- Liver Transplantation
(physiology)
- Male
- Middle Aged
- Prostate-Specific Antigen
(blood)
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