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[Mycobacterial antigens and antitubercular antibodies in patients with tuberculosis salpingo-oophoritis].

Abstract
Sixty two and 59 patients with tuberculous and nontuberculous salpingo-oophoritis, respectively, and 30 healthy females were examined. It was found that indirect solid-phase enzyme immunoassay (EIA) using ultrasonography of Mycobacterium tuberculosis H37Rv could detect antituberculosis antibodies in 66.7% of patients with tuberculous salpingo-oophoritis, and in 10% of healthy females. That using the antigen isolated from the cell wall extract of M. tuberculosis (whose molecular weight was 38 - 42 kD) could reveal them in 70.2, 4.3%, and 6.7%, respectively. After dissociation of immune complexes, EIA inhibition using affinity-purified antimycobacterial antisera displayed mycobacterial antigens in 75.0 and 4.3% of patients with tuberculous and nontuberculous salpingo-oophoritis, respectively, and in none healthy female. Thus, the detection of mycobacterial antigens and antituberculosis antibody may be successfully used in the complex diagnosis of tuberculosis of the female genitals.
AuthorsA B Bazarova, A V Baenskií, N V Kulikovskaia, V I Litvinov
JournalProblemy tuberkuleza (Probl Tuberk) Issue 4 Pg. 26-8 ( 1997) ISSN: 0032-9533 [Print] Russia (Federation)
Vernacular TitleAntigeny mikobakterií i protivotuberkuleznye antitela u bol'nykh tuberkuleznym sal'pingooforitom.
PMID9333811 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Tuberculin
Topics
  • Adnexa Uteri (microbiology)
  • Adult
  • Antibodies, Bacterial (analysis)
  • Antigens, Bacterial (analysis)
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Middle Aged
  • Mycobacterium tuberculosis (immunology)
  • Oophoritis (diagnosis, immunology, microbiology)
  • Salpingitis (diagnosis, immunology, microbiology)
  • Tuberculin (analysis)
  • Tuberculosis (complications, diagnosis, immunology)

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