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Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections.

Abstract
The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.
AuthorsP Ringwald, J Bickii, A Same-Ekobo, L K Basco
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 41 Issue 10 Pg. 2317-9 (Oct 1997) ISSN: 0066-4804 [Print] United States
PMID9333075 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antimalarials
  • Naphthyridines
  • Tablets, Enteric-Coated
  • pyronaridine
Topics
  • Adolescent
  • Adult
  • Animals
  • Antimalarials (administration & dosage, therapeutic use)
  • Child
  • Female
  • Humans
  • Malaria (drug therapy, parasitology)
  • Male
  • Naphthyridines (administration & dosage, therapeutic use)
  • Plasmodium
  • Plasmodium malariae
  • Tablets, Enteric-Coated

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