Cisplatin and acute tubular necrosis.

Abstract

We report an unusually short lived and asymptomatic episode of severe cisplatin-induced renal tubular salt wasting in a fit 41-year-old patient with malignant teratoma. This was associated with polyuria but no significant hyponatraemia. Full recovery occurred because of early pick up, emphasizing the need for careful fluid balance monitoring of patients receiving cisplatin chemotherapy.

• Authors: N J Wadd, C Tiplady, J T Roberts
• Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) (Clin Oncol (R Coll Radiol)) Vol. 9 Issue 4 Pg. 267-8 ( 1997) ISSN: 0936-6555 [Print] England
• PMID: 9315405 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Cisplatin

Topics

• Adult
• Antineoplastic Agents (adverse effects)
• Cisplatin (adverse effects)
• Humans
• Kidney Tubular Necrosis, Acute (chemically induced, diagnosis)
• Male
• Teratoma (drug therapy)
• Testicular Neoplasms (drug therapy)