Bioactivity of ferrimagnetic glass-ceramics in the system FeO-Fe2O3-CaO-SiO2.

Abstract

Bioactive and ferrimagnetic glass-ceramics are useful as thermoseeds for hyperthermia treatment of cancer. A heat treatment of a 40(FeO, Fe2O3)-60CaO x SiO2 wt% glass gives a ferrimagnetic glass-ceramic containing 36 wt% magnetite in a CaO x SiO2 matrix. However, it does not show bioactivity since a small amount of iron ion remains in the matrix. In the present study, bioactivities of ferrimagnetic glass-ceramics which were prepared by heat treatment of glasses of the composition 40(FeO, Fe2O3)-60CaO x SiO2 (wt%) with various components added at 100:3 weight ratio were evaluated in vitro by examining bone-like apatite formation on their surfaces in a simulated body fluid. It was found that glass-ceramics with Na2O or B2O3 added in combination with P2O5 show bioactivity.

• Authors: Y Ebisawa, F Miyaji, T Kokubo, K Ohura, T Nakamura
• Journal: Biomaterials (Biomaterials) Vol. 18 Issue 19 Pg. 1277-84 (Oct 1997) ISSN: 0142-9612 [Print] Netherlands
• PMID: 9307216 (Publication Type: Journal Article)

Chemical References

• Apatites
• Biocompatible Materials
• Bone Substitutes
• Ferric Compounds
• Oxides
• ferrite
• Glass ceramics
• Iron
• Ferrosoferric Oxide

Topics

• Apatites (metabolism)
• Biocompatible Materials (chemistry, metabolism)
• Bone Substitutes (chemistry, metabolism)
• Ceramics (chemistry, metabolism)
• Ferric Compounds (chemistry)
• Ferrosoferric Oxide
• Hot Temperature
• Humans
• Iron (chemistry)
• Oxides (chemistry)
• Plasma (chemistry, metabolism)
• X-Ray Diffraction