Complete remission in three patients with acute myeloblastic leukemia by administration of G-CSF without antileukemic agents.

We describe 3 patients with acute myeloblastic leukemia (AML), who received rhG-CSF for infections such as pneumonia or for prophylaxis of infection, and who achieved complete remission. They had not received any antileukemic therapy before or during the administration of rhG-CSF. These findings suggest the possibility that complete remission can be brought about by G-CSF itself in some patients with AML.
AuthorsM Takahashi, T Koike, Y Aizawa, M Kashimura, K Hayatsu, K Nagai, A Abe, M Urushiyama, K Yagisawa
JournalAmerican journal of hematology (Am J Hematol) Vol. 56 Issue 1 Pg. 42-4 (Sep 1997) ISSN: 0361-8609 [Print] UNITED STATES
PMID9298867 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Recombinant Proteins
  • Granulocyte Colony-Stimulating Factor
  • Aged
  • Bacterial Infections (etiology, prevention & control)
  • Granulocyte Colony-Stimulating Factor (therapeutic use)
  • Humans
  • Leukemia, Myeloid, Acute (complications, drug therapy, physiopathology)
  • Male
  • Middle Aged
  • Recombinant Proteins (therapeutic use)
  • Remission Induction

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