Reflux esophagitis after proximal subtotal gastrectomy.

Carcinoma of the cardia of stomach or carcinoma of the esophagocardiac (EC) junction has a poor prognosis. Proximal subtotal gastrectomy is often performed for a smaller tumor. It achieves a prognosis similar to that of total gastrectomy and prevents pernicious anemia. A better functional result was expected than that total gastrectomy did from us, but the clinical observation was surprising. Most patients had symptoms of reflux esophagitis after surgery. All of these patients were reevaluated.
From November, 1990 to March, 1996, there were 27 patients who received proximal subtotal gastrectomy at this hospital. Twenty of these were involved in this study. Floppy Nissen's fundoplication was performed during operation as a anti-reflux procedure. Continuous 24-h pH monitoring, esophageal manometry, and endoscopic examination were performed for study.
Most of the patients had symptoms of gastroesophageal reflux. 80% (16/20) of the patients were found to have reflux esophagitis under endoscopy. The patients had higher pH scores (mean 85.8 +/- 45.6) than normal (< 17.5), lower pressure of LES (8.03 +/- 7.01 mmHg), shorter total lengths (mean 1.60 +/- 0.56 cm) and intraabdominal lengths (mean 1.29 +/- 0.30 cm) of new lower esophageal sphincters.
Clearly there was failure to prevent reflux esophagitis through floppy Nissen's fundoplication. Severe gastroesophageal reflux did appear after proximal gastric resection. A gastric remnant with safe cut-margin is often too short to perform complete wrapping. Proximal subtotal gastrectomy is not recommended for early cancer of the cardia of the stomach.
AuthorsC Y Wang, H K Hsu, H C Chang, M S Huang, Y G Goan, J M Su
JournalZhonghua yi xue za zhi = Chinese medical journal; Free China ed (Zhonghua Yi Xue Za Zhi (Taipei)) Vol. 59 Issue 6 Pg. 348-53 (Jun 1997) ISSN: 0578-1337 [Print] China (Republic : 1949- )
PMID9294914 (Publication Type: Journal Article)
  • Aged
  • Aged, 80 and over
  • Esophagitis, Peptic (etiology)
  • Female
  • Gastrectomy (adverse effects)
  • Gastric Acidity Determination
  • Humans
  • Male
  • Middle Aged

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