Abstract |
The nucleotide sequence of two open reading frames (ORFs) from Thermoanaerobacterium thermosulfurigenes EM1 was determined that encode proteins with similarity to components of ATP-binding cassette (ABC) transport systems. Sequence analysis suggests that the deduced proteins AbcA and AbcB consist of an NH2-terminal membrane-spanning domain and a COOH-terminal ATP-binding domain. The deduced proteins AbcA and AbcB showed highest similarity to proteins of the MsbA subfamily of ABC transporters. AbcA and AbcB probably function as a heterodimer. An ORF predicted to encode the primary sigma factor SigA was identified downstream of abcB.
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Authors | M Matuschek, K Sahm, H Bahl |
Journal | Current microbiology
(Curr Microbiol)
Vol. 35
Issue 4
Pg. 237-9
(Oct 1997)
ISSN: 0343-8651 [Print] United States |
PMID | 9290065
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- ATP-Binding Cassette Transporters
- Bacterial Proteins
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Topics |
- ATP-Binding Cassette Transporters
(chemistry, genetics)
- Amino Acid Sequence
- Bacteria, Anaerobic
(genetics)
- Bacterial Proteins
(chemistry, genetics)
- Chromosome Mapping
- Cloning, Molecular
- Genes, Bacterial
- Molecular Sequence Data
- Open Reading Frames
- Sequence Homology, Amino Acid
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