HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[MRI dacryocystography after applying gadolinium-containing eyedrops].

AbstractPURPOSE:
To determine the efficacy of MRI for the lacrimal drainage system after conjunctival application of gadolinium-DTPA solution.
MATERIAL AND METHODS:
MRI dacryocystography of 32 nasolacrimal duct systems was performed in 16 patients additional to digital subtraction dacryocystography. The gadolinium solution was prepared by diluting the commercially available gadolinium-DTPA (Magnevist, Schering AG, Berlin) 1:10 in sterile saline solution. 3 x 2 drops of this contrast medium were instilled bilaterally immediately before MRI scanning.
RESULTS:
MRI dacryocystography provided detailed information on the nasolacrimal duct system in all 32 cases. In 16 cases localisation and functional degree of nasolacrimal duct obstruction or stenosis was determined reliably. In 15 cases normal nasolacrimal duct system showed no contrast enhancement. In one case stenosis of the canaliculus was observed.
CONCLUSION:
MRI dacryocystography provides detailed morphological soft tissue information of the lacrimal drainage system. Local conjunctival application of gadolinium solution allows functional tests of the lacrimal duct system in patients suffering from epiphora.
AuthorsK Wilhelm, E Keller, J Textor, E Walther, H Schüller, H Schild
JournalRoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin (Rofo) Vol. 167 Issue 1 Pg. 58-61 (Jul 1997) ISSN: 1438-9029 [Print] Germany
Vernacular TitleMRT-Dakryozystographie nach Applikation gadoliniumhaltiger Augentropfen.
PMID9289044 (Publication Type: Journal Article)
Chemical References
  • Contrast Media
  • Ophthalmic Solutions
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium
  • Gadolinium DTPA
Topics
  • Adult
  • Aged
  • Angiography, Digital Subtraction
  • Conjunctiva
  • Contrast Media (administration & dosage)
  • Female
  • Gadolinium (administration & dosage)
  • Gadolinium DTPA
  • Humans
  • Lacrimal Apparatus (diagnostic imaging, pathology)
  • Lacrimal Apparatus Diseases (diagnosis)
  • Magnetic Resonance Imaging (methods)
  • Male
  • Middle Aged
  • Ophthalmic Solutions
  • Organometallic Compounds (administration & dosage)
  • Pentetic Acid (administration & dosage, analogs & derivatives)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: