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Transvaginal interstitial laser treatment of the ovary for the management of chronic hyperandrogenic anovulation: first clinical experience.

Abstract
The feasibility of ultrasound-guided transvaginal interstitial laser treatment of the ovary (TILT) and its efficacy for ovulation induction was investigated in 3 hormone-therapy-resistant patients with chronic hyperandrogenic anovulation. TILT was performed at powers of 1-2 W and exposures of 75-600 s. Clear-cut hyperechogenic zones developed during laser irradiation with diameters of up to 13.7 mm. Spontaneous ovulation and/or hormonal changes after TILT did not occur. No adhesion formation was seen during a laparoscopy or laparotomy in 2 patients 6 months after TILT. In conclusion, TILT of the ovaries was simple to perform but so far the clinical results are disappointing. Further studies with a modified technique are necessary to further investigate the efficacy of TILT.
AuthorsE M Kaaijk, F van der Veen, J F Beek, M J van Gemert, F B Lammes
JournalGynecologic and obstetric investigation (Gynecol Obstet Invest) Vol. 44 Issue 2 Pg. 115-9 ( 1997) ISSN: 0378-7346 [Print] Switzerland
PMID9286725 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adult
  • Anovulation (etiology, surgery)
  • Female
  • Humans
  • Hyperandrogenism (complications, surgery)
  • Infertility, Female (surgery)
  • Laser Therapy (methods)
  • Ovary (surgery, ultrastructure)
  • Pilot Projects

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