Abstract | OBJECTIVE: DESIGN: Longitudinal study between months 6 and 12 after transplant, in 80 cyclosporine-treated heart, liver and kidney transplant patients. SETTING: Madrid Puerta de Hierro Hospital. SUBJECTS AND METHODS: The 37 patients who had developed overgrowth in the sixth month were randomly split into three study groups. The remaining 43 were split into two additional groups. INTERVENTIONS: The first group underwent professional cleaning; the second underwent, additionally, scaling and root planing, and the third group received no treatment. The fourth and the fifth groups received no treatment and professional cleaning, respectively. MAIN OUTCOME MEASURES: RESULTS: A significant (P = 0.008) increase in overgrowth was found in the third group that did not undergo treatment. Significantly (P = 0.002) less was found in the first and second groups. Highly significant (P = 0.001) reductions in the plaque and gingivitis indices were also found in these two groups. The fifth group showed a highly significant (P = 0.0001) decrease in the plaque and gingivitis indices. CONCLUSIONS:
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Authors | M L Somacarrera, M Lucas, C Scully, C Barrios |
Journal | British dental journal
(Br Dent J)
Vol. 183
Issue 3
Pg. 89-94
(Aug 09 1997)
ISSN: 0007-0610 [Print] England |
PMID | 9282449
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Immunosuppressive Agents
- Cyclosporine
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Topics |
- Adult
- Cyclosporine
(adverse effects)
- Dental Plaque
(pathology, prevention & control)
- Dental Plaque Index
- Dental Prophylaxis
- Dental Scaling
- Evaluation Studies as Topic
- Female
- Follow-Up Studies
- Gingival Overgrowth
(chemically induced, pathology, prevention & control)
- Gingivitis
(pathology, prevention & control)
- Heart Transplantation
- Humans
- Immunosuppressive Agents
(adverse effects)
- Kidney Transplantation
- Liver Transplantation
- Longitudinal Studies
- Male
- Periodontal Index
- Root Planing
- Treatment Outcome
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