Isolated venlafaxine-induced serotonin syndrome.

Abstract

Serotonin syndrome is a potentially fatal complication of serotonergic drug therapy. Usually, serotonin syndrome occurs with the concomitant use of two serotonergic drugs; this case report describes a patient with a classic presentation of serotonin syndrome induced solely by a venlafaxine overdose. Emergency physicians need to be aware that the serotonin syndrome may occur not only with serotonergic drug combinations but also with overdoses of a single potent serotonergic agent such as venlafaxine.

• Authors: P Kolecki
• Journal: The Journal of emergency medicine (J Emerg Med) 1997 Jul-Aug Vol. 15 Issue 4 Pg. 491-3 ISSN: 0736-4679 [Print] United States
• PMID: 9279702 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cyclohexanols
• Serotonin Uptake Inhibitors
• Venlafaxine Hydrochloride

Topics

• Adult
• Autonomic Nervous System Diseases (chemically induced, diagnosis, therapy)
• Cyclohexanols (poisoning)
• Drug Overdose
• Humans
• Male
• Neuromuscular Diseases (chemically induced, diagnosis, therapy)
• Selective Serotonin Reuptake Inhibitors (poisoning)
• Substance-Related Disorders (diagnosis, etiology, therapy)
• Syndrome
• Venlafaxine Hydrochloride