Vitamin K-responsive coagulopathy in Henoch-Schölein purpura.

Abstract

Henoch-Schönlein purpura is classically described as a systemic vasculitis without known platelet or clotting abnormality. A 15-year-old boy with Henoch-Schönlein purpura experienced a major hemorrhagic diathesis that was responsive to parenterally administered vitamin K. We believe that the gastrointestinal vasculitis prevented the absorption of available vitamin K necessary for the synthesis of clotting factors. Early treatment with parenteral vitamin K in similar cases should be considered.

• Authors: S L McNairy, J L Millns, R L Phyliky, R S Rogers 3rd
• Journal: Mayo Clinic proceedings (Mayo Clin Proc) Vol. 52 Issue 11 Pg. 746-7 (Nov 1977) ISSN: 0025-6196 [Print] England
• PMID: 926852 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vitamin K

Topics

• Adolescent
• Blood Coagulation Disorders (drug therapy, etiology)
• Humans
• IgA Vasculitis (complications)
• Male
• Vitamin K (therapeutic use)