Abstract | BACKGROUND AND STUDY AIMS:
Tumor ingrowth through self-expanding metal stents presents a difficult problem for management. The techniques for treating tumor ingrowth have not yet been well described, and the optimal endoscopic approach is not clear. We have recently used photodynamic therapy ( PDT) to treat tumor ingrowth through uncovered nitinol mesh stents. PATIENTS AND METHODS: Four patients (mean age 73) with obstructive adenocarcinomas of the distal esophagus had received self-expanding stents for palliation of their dysphagia. After stent placement, tumor ingrowth had caused progressive dysphagia in all of the patients; the dysphagia was graded on a scale from 0 (normal) to 4 (inability to swallow liquids). All of the patients received PDT treatment. RESULTS: After PDT, excellent palliation of the dysphagia was seen in all of the patients, with a mean improvement in the dysphagia score of 2.25 and a mean dysphagia-free interval of 92 days. There were no major complications. CONCLUSION: The use of PDT to treat tumor ingrowth through self-expanding metal esophageal stents is effective and safe.
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Authors | D M Scheider, M Siemens, M Cirocco, G B Haber, G Kandel, P Kortan, N E Marcon |
Journal | Endoscopy
(Endoscopy)
Vol. 29
Issue 4
Pg. 271-4
(May 1997)
ISSN: 0013-726X [Print] Germany |
PMID | 9255530
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Alloys
- Photosensitizing Agents
- nitinol
- Hematoporphyrin Derivative
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Topics |
- Adenocarcinoma
(complications, mortality, therapy)
- Aged
- Aged, 80 and over
- Alloys
(adverse effects)
- Deglutition Disorders
(etiology, prevention & control)
- Esophageal Neoplasms
(complications, mortality, therapy)
- Esophageal Stenosis
(etiology, prevention & control)
- Esophagoscopy
- Female
- Foreign-Body Reaction
(etiology, prevention & control)
- Hematoporphyrin Derivative
(therapeutic use)
- Humans
- Male
- Middle Aged
- Palliative Care
(methods)
- Photochemotherapy
- Photosensitizing Agents
(therapeutic use)
- Prognosis
- Stents
(adverse effects)
- Survival Rate
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