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[Use of mannitol and propranolol in the treatment of experimental acute renal failure (histomorphological study)].

Abstract
Experimental research was carried out in order to ascertain whether administration of drugs capable of acting on the renal circulation, such as mannitol and propanol, in addition to improving the renal function, also have a protective effect on the histomorphological alterations induced by the acute renal ischemia. On the basis of the results of the research the Authors conclude by asserting that the combined use of mannitol and propanol has a real protective effect in preventing or attenuating lesions of the kidney caused by serious acute renal failure.
AuthorsP Melita, A Motta, A Arsena, L Calbo, C Micali, V De Leo
JournalChirurgia italiana (Chir Ital) Vol. 29 Issue 2 Pg. 200-14 (Apr 1977) ISSN: 0009-4773 [Print] Italy
Vernacular TitleL'impiego del mannitolo e del prophanololo nel trattamento dell'insufficienza renale acuta sperimental e (studio istomorfologico).
PMID922999 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Mannitol
  • Propranolol
Topics
  • Acute Kidney Injury (drug therapy, pathology)
  • Animals
  • Dogs
  • Female
  • Kidney (pathology)
  • Male
  • Mannitol (therapeutic use)
  • Propranolol (therapeutic use)

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