[The effect of polyunsaturated fatty acids of the omega-3 class on the late phase of the allergic reaction in bronchial asthma patients].

Abstract

Placebo-controlled study of changes in the course of atopic bronchial asthma (ABA) induced by supplement of the diet with polyunsaturated fatty acids of omega-3 class in 13 patients compared to placebo-treated subjects allowed the conclusion on significant attenuation of late allergic response in patients who had taken eiconol for two weeks. The effects of the acids are explained by a comparative replacement of arachidonic acid in the membranes of cell effectors of the inflammation with omega-3 fatty acids leading to inhibition of production of inflammation lipid mediators.

• Authors: K A Masuev
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 69 Issue 3 Pg. 31-3 ( 1997) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Vliianie polinenasyshchennykh zhirnykh kislot omega-3 klassa na pozdniuiu fazu allergicheskoĭ reaktsii y bol'nykh bronkhial'noĭ astmoĭ.
• PMID: 9229824 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Allergens
• Anti-Asthmatic Agents
• Dietary Fats, Unsaturated
• Dust
• Fish Oils
• eiconol

Topics

• Adolescent
• Adult
• Allergens
• Anti-Asthmatic Agents (therapeutic use)
• Asthma (diagnosis, drug therapy)
• Chronic Disease
• Dietary Fats, Unsaturated (therapeutic use)
• Drug Evaluation
• Dust (adverse effects)
• Fish Oils (therapeutic use)
• Humans
• Respiratory Hypersensitivity (diagnosis, drug therapy)
• Time Factors