Abstract | BACKGROUND: METHOD: RESULTS: Both hyponatremia and hypouricemia were demonstrated in the presence of SIADH in one patient, during an episode of acute water intoxication in another, and in association with chronic hyponatremia in a patient who was following the target weight procedure. Elevated fractional excretion of uric acid percentage (FEUA%) was detected in two patients. These states appeared to be episodic or transitory. In the five patients with simple polydipsia, serum uric acid concentrations and FEUA% were maintained within the normal range. CONCLUSION: Altered uric acid regulation that resembles SIADH is present in patients with polydipsia- hyponatremia syndrome. Monitoring the uric acid concentration and FEUA% in polydipsic patients may be useful in identifying those patients with transiently impaired water excretion.
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Authors | T Hanihara, I Amagai, H Hagimoto, Y Makimoto |
Journal | The Journal of clinical psychiatry
(J Clin Psychiatry)
Vol. 58
Issue 6
Pg. 256-60
(Jun 1997)
ISSN: 0160-6689 [Print] United States |
PMID | 9228891
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Drinking
- Humans
- Hyponatremia
(blood)
- Inappropriate ADH Syndrome
(blood, complications)
- Male
- Middle Aged
- Osmolar Concentration
- Schizophrenia
(blood, complications, urine)
- Schizophrenic Psychology
- Sodium
(blood)
- Specific Gravity
- Uric Acid
(blood)
- Urine
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