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Systemic involvement in scleredema of Buschke associated with IgG-kappa paraproteinaemia.

Abstract
Scleredema is a rare primary cutaneous mucinosis. Systemic involvement is uncommon and histological confirmation is often lacking. We report a case of a 60-year-old man with scleredema and evidence of mucin deposition on biopsies from multiple extracutaneous sites. The bone marrow, nerve, hepatic and salivary gland involvement seen on histology in our patient has not, to our knowledge, been previously reported in this condition.
AuthorsT Basarab, N P Burrows, S E Munn, R Russell Jones
JournalThe British journal of dermatology (Br J Dermatol) Vol. 136 Issue 6 Pg. 939-42 (Jun 1997) ISSN: 0007-0963 [Print] England
PMID9217831 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunoglobulin G
Topics
  • Bone Marrow (pathology)
  • Humans
  • Immunoglobulin G
  • Liver (pathology)
  • Male
  • Middle Aged
  • Mouth Mucosa (pathology)
  • Nerve Tissue (pathology)
  • Paraproteinemias (complications, pathology)
  • Salivary Glands (pathology)
  • Scleredema Adultorum (immunology, pathology)
  • Skin (pathology)

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