HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Gene therapy for lysosomal storage disease: a no-brainer? Transplants of fibroblasts secreting high levels of beta-glucuronidase decrease lesions in the brains of mice with Sly syndrome, a lysosomal storage disease.

AuthorsW S Sly, C Vogler
JournalNature medicine (Nat Med) Vol. 3 Issue 7 Pg. 719-20 (Jul 1997) ISSN: 1078-8956 [Print] United States
PMID9212092 (Publication Type: Comment, News)
Chemical References
  • Glycosaminoglycans
  • Receptor, IGF Type 2
  • Glucuronidase
Topics
  • Animals
  • Brain (metabolism)
  • Fibroblasts (metabolism, transplantation)
  • Genetic Therapy
  • Glucuronidase (genetics, metabolism)
  • Glycosaminoglycans (metabolism)
  • Humans
  • Mice
  • Mucopolysaccharidosis VII (therapy)
  • Receptor, IGF Type 2 (metabolism)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: