Evaluation of renal artery stenosis with dynamic gadolinium-enhanced MR angiography.

Abstract

OBJECTIVE:

The purpose of this study was to compare dynamic gadolinium-enhanced three-dimensional spoiled gradient-recalled MR angiography with conventional arteriography in the evaluation of proximal renal artery stenosis (RAS).

MATERIALS AND METHODS:

MR angiography and conventional arteriographic examinations of 30 patients evaluated for RAS were analyzed retrospectively. Three-dimensional MR angiography was performed with an RF spoiled gradient-recalled imaging sequence acquired during the dynamic i.v. injection of gadolinium (0.2-0.3 mmol/kg), MR data and conventional arteriograms were independently evaluated for the number and location of renal arteries and the degree and location of stenoses. The patients had a mean age of 70 years old and a mean serum creatinine level of 2.9 mg/dl, reflecting a population in whom atherosclerotic RAS was the primary concern.

RESULTS:

Gadolinium-enhanced MR angiography revealed 100% of main renal arteries. For RAS of 50% or greater occlusion, the technique was 100% sensitive and 71% specific; the negative predictive value was 100%. The technique was 100% sensitive and 71% specific for RAS of 75% or greater occlusion.

CONCLUSION:

Dynamic gadolinium-enhanced three-dimensional spoiled gradient-recalled MR angiography has a high sensitivity for revealing proximal RAS and is a quick and reliable technique for obtaining helpful anatomic information.

• Authors: M J Rieumont, J A Kaufman, S C Geller, E K Yucel, R P Cambria, L S Fang, H Bazari, A C Waltman
• Journal: AJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 169 Issue 1 Pg. 39-44 (Jul 1997) ISSN: 0361-803X [Print] United States
• PMID: 9207498 (Publication Type: Journal Article)

Chemical References

• Contrast Media
• Drug Combinations
• Organometallic Compounds
• Meglumine
• Pentetic Acid
• gadodiamide
• Gadolinium
• Gadolinium DTPA

Topics

• Aged
• Aged, 80 and over
• Contrast Media
• Drug Combinations
• Female
• Gadolinium
• Gadolinium DTPA
• Humans
• Image Processing, Computer-Assisted
• Magnetic Resonance Angiography
• Male
• Meglumine
• Middle Aged
• Organometallic Compounds
• Pentetic Acid (analogs & derivatives)
• Radiography
• Renal Artery (diagnostic imaging, pathology)
• Renal Artery Obstruction (diagnosis, diagnostic imaging)
• Retrospective Studies
• Sensitivity and Specificity