[Importance of the delayed 123I-BMIPP image for detecting myocardial metabolic abnormality induced by transient myocardial ischemia: a case of vasospastic angina].

We experienced a case of 64-year-old man with stunned myocardium caused by vasospasm. Without enzymatic evidence of an acute myocardial infarction, the patient developed a prolonged chest pain with ST elevation in the electrocardiogram in the midnight before the day of coronary angiography. Coronary angiogram revealed no significant stenosis and left ventriculography demonstrated akinesis in the apico-anteroseptal region. Although initial images of 123I-BMIPP myocardium SPECT showed no significant decrease of uptake, delayed images revealed marked decrease of tracer uptake in the apico-anteroseptal region in which left ventriculography showed abnormal wall motion. After 3 months of medication, left ventriculography disclosed a marked improvement, and coronary spasm was evoked in the proximal portion of left anterior descending artery after intracoronary ergonovine provocations. At the same time, both initial and delayed images of 123I-BMIPP myocardial SPECT showed no significant decrease of tracer uptake. This patients was considered as a noteworthy case to understand the kinetics and metabolism of 123I-BMIPP in stunned myocardium.
AuthorsK Tanaka, K Ito, N Kinoshita, M Nakagawa, K Terada, Y Kajita, H Sugihara
JournalKaku igaku. The Japanese journal of nuclear medicine (Kaku Igaku) Vol. 34 Issue 4 Pg. 229-35 (Apr 1997) ISSN: 0022-7854 [Print] JAPAN
PMID9183146 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Fatty Acids
  • Iodine Radioisotopes
  • Iodobenzenes
  • iodofiltic acid
  • Angina Pectoris (radionuclide imaging)
  • Coronary Vasospasm (radionuclide imaging)
  • Fatty Acids (pharmacokinetics)
  • Humans
  • Iodine Radioisotopes (pharmacokinetics)
  • Iodobenzenes (pharmacokinetics)
  • Male
  • Middle Aged
  • Myocardial Stunning (radionuclide imaging)
  • Myocardium (metabolism)
  • Tomography, Emission-Computed, Single-Photon

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