[The pharmacological effect of betapressin in hypertension].

Abstract

The work analyses the results of treating 20 hypertensive patients with (stage I-II) with betapressin. The drug is shown to be active in causing a significant decrease of systolic and mean arterial pressure. Its hypotensive effect is associated with essential decrease of peripheral vascular resistance. This circumstance, as well as acceleration of the heart rhythm, leads to increase of the cardiac output. Betapressin is recommended for monotherapy of patients suffering from stages I-II hypertension with eu- and hypokinetic types of hemodynamics.

• Authors: R M Zaslavskaia, K Zh Akhmetov, V A Gol'denberg, G V Lilitsa
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 1996 Nov-Dec Vol. 59 Issue 6 Pg. 23-5 ISSN: 0869-2092 [Print] Russia (Federation)
• Vernacular Title: Farmakologicheskiĭ éffekt betapressina pri gipertonicheskoĭ bolezni.
• PMID: 9181866 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antihypertensive Agents
• Penbutolol

Topics

• Adult
• Analysis of Variance
• Antihypertensive Agents (administration & dosage, pharmacology)
• Chronic Disease
• Drug Evaluation
• Female
• Hemodynamics (drug effects)
• Humans
• Hypertension (drug therapy, physiopathology)
• Male
• Middle Aged
• Penbutolol (administration & dosage, pharmacology)