Effect of niuche-shen-qi-wan on painful muscle cramps in patients with liver cirrhosis: a preliminary report.

Abstract

Twelve patients with liver cirrhosis complaining of painful muscle cramps were treated with Niuche-Shen-Qi-Wan (TJ-107). Three patients were at the decompensated state. Muscle cramps disappeared in 4 weeks on the average after oral administration of TJ-107 in all 12 patients. During the period of TJ-107 administration, there was no significant improvement of hepatic function. One patient complained of mild epigastric discomfort after taking TJ-107, but there were no other adverse effects. Our results indicate that TJ-107 is useful for treatment of painful muscle cramps in cirrhotic patients.

• Authors: Y Motoo, H Taga, Y Yamaguchi, H Watanabe, T Okai, N Sawabu
• Journal: The American journal of Chinese medicine (Am J Chin Med) Vol. 25 Issue 1 Pg. 97-102 ( 1997) ISSN: 0192-415X [Print] Singapore
• PMID: 9167002 (Publication Type: Case Reports, Clinical Trial, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Cholagogues and Choleretics
• Diuretics
• Drugs, Chinese Herbal
• Plant Extracts
• sairei-to
• Vitamin B Complex
• saiko-keishi-to
• Ursodeoxycholic Acid

Topics

• Administration, Oral
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage, pharmacology, therapeutic use)
• Cholagogues and Choleretics (pharmacology, therapeutic use)
• Diuretics (administration & dosage, therapeutic use)
• Drugs, Chinese Herbal (administration & dosage, pharmacology, therapeutic use)
• Female
• Humans
• Liver Cirrhosis (complications, drug therapy, physiopathology)
• Male
• Middle Aged
• Muscle Cramp (drug therapy, etiology)
• Plant Extracts (administration & dosage, pharmacology, therapeutic use)
• Plants, Medicinal (metabolism)
• Treatment Outcome
• Ursodeoxycholic Acid (administration & dosage, therapeutic use)
• Vitamin B Complex (administration & dosage, therapeutic use)