Abstract | BACKGROUND: METHODS:
Baralyme was dried to constant weight. Carbon monoxide formation from desflurane and desiccated Baralyme was determined in sealed 20.7-ml vials without adding water, after adding 10% of the normal water content (1.3% water), and after adding 100% of the normal water content (13% water) to the dry absorbent. Similar measurements were made using an anesthesia machine and circle system. Carbon monoxide was measured by gas chromatography-mass spectrometry. RESULTS:
Carbon monoxide formation from desflurane in vitro was decreased from 10,700 ppm with desiccated Baralyme to 715 ppm and less than 100 ppm, respectively, when 1.3% and 13% water were added. Complete rehydration also decreased CO formation from enflurane and isoflurane to undetectable concentrations. Desflurane degradation in an anesthesia machine produced 2,500 ppm CO in the circuit, which was reduced to less than 180 ppm when the full complement of water (13%) was added to the dried absorbent. CONCLUSIONS:
|
Authors | P J Baxter, E D Kharasch |
Journal | Anesthesiology
(Anesthesiology)
Vol. 86
Issue 5
Pg. 1061-5
(May 1997)
ISSN: 0003-3022 [Print] United States |
PMID | 9158355
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Anesthetics, Inhalation
- Barium Compounds
- Potassium Compounds
- Baralyme
- Carbon Monoxide
- Desflurane
- Isoflurane
- Calcium Hydroxide
|
Topics |
- Anesthesia, Inhalation
(instrumentation)
- Anesthetics, Inhalation
(chemistry)
- Barium Compounds
(chemistry)
- Calcium Hydroxide
(chemistry)
- Carbon Monoxide
(chemical synthesis)
- Desflurane
- Desiccation
- Isoflurane
(analogs & derivatives, chemistry)
- Potassium Compounds
(chemistry)
|