Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: clinical, radiological and histological pattern.

Abstract

The most common lung tissue reaction to amiodarone toxicity is a nonspecific pulmonary chronic interstitial pneumonia. In a minority of patients diffuse alveolar damage, alveolar haemorrhage or bronchiolitis obliterans organizing pneumonia (BOOP) is encountered. We report the case of a patient with clinical, functional, radiological and histological signs of BOOP secondary to amiodarone. The condition was partially reversible after suspending drug treatment, and resolved after corticosteroid treatment without relapse after a 14 month follow-up.

• Authors: S C Conte, V Pagan, B Murer
• Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace (Monaldi Arch Chest Dis) Vol. 52 Issue 1 Pg. 24-6 (Feb 1997) ISSN: 1122-0643 [Print] Italy
• PMID: 9151516 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Amiodarone

Topics

• Aged
• Amiodarone (adverse effects, therapeutic use)
• Anti-Arrhythmia Agents (adverse effects, therapeutic use)
• Cryptogenic Organizing Pneumonia (chemically induced, diagnosis)
• Humans
• Lung (diagnostic imaging, pathology)
• Male
• Radiography