HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Midline glossectomy and epiglottidectomy for obstructive sleep apnea syndrome.

Abstract
Obstructive sleep apnea syndrome is caused by narrowing of the pharyngeal airway and loss of dilator tone during sleep. In patients with severe apnea surgical correction often requires attention to both the oropharynx and hypopharynx. Tongue reduction surgery has been described for persistent apnea after failure of palatal surgery. We describe our experience with midline glossectomy with epiglottidectomy in 12 patients with a mean age of 48.8 +/- 14.2 years and body mass index of 36.0 +/- 8.8 kg/m2. Response to treatment was defined as a postoperative respiratory disturbance index (RDI) below 20. Three patients (25%) responded to treatment. The mean apnea index decreased from 48.9 to 35.7, RDI decreased from 73.3 to 46.6, and lowest oxygen saturation increased from 65.9 to 77.9%. RDI in responders decreased from 69.7 to 10. Midline glossectomy with epiglottidectomy has variable results, yet is effective in selected patients with hypopharyngeal narrowing related to macroglossia.
AuthorsS A Mickelson, L Rosenthal
JournalThe Laryngoscope (Laryngoscope) Vol. 107 Issue 5 Pg. 614-9 (May 1997) ISSN: 0023-852X [Print] United States
PMID9149162 (Publication Type: Clinical Trial, Journal Article)
Topics
  • Adult
  • Aged
  • Epiglottis (surgery)
  • Female
  • Fiber Optic Technology
  • Glossectomy (methods)
  • Humans
  • Laryngoscopy
  • Length of Stay
  • Male
  • Middle Aged
  • Sleep Apnea Syndromes (diagnosis, physiopathology, surgery)
  • Sleep, REM (physiology)
  • Tracheotomy
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: