Red palm oil as a source of beta-carotene for combating vitamin A deficiency.

Twenty four school children of 7-9 years of age were divided into two groups of six boys and six girls each. One group was given a daily supplement of 'Suji halwa', a sweet snack made with semolina and red palm oil, supplying 2400 mu g of beta-carotene and the second group was the control group which was given 600 mu g of oral vitamin A palmitate, for 60 days. Vitamin A status before and after supplementation was assessed by the Modified Relative Dose Response Assay (MRDR). Results indicated that serum vitamin A levels increased from the basal level of 0.86 +/- 0.13 mu m mol/l to 1.891 +/- 0.23 mu mol/l in the Red Palmoil (RPO) group and from 0.74 +/- 0.09 to 1.94 +/- 0.21 mu mol/l in the control vitamin A group. Dehydroretinol/Retinol (DR/R) ratio decreased from 0.073 +/- 0.025 to 0.023 +/- 0.004 in the RPO group and from 0.090 +/- 0.023 to 0.023 +/- 0.004 in the vitamin A group, indicating liver saturation with vitamin A after feeding RPO snacks, comparable to synthetic vitamin A. This study indicates that RPO is an efficient source of beta-carotene which is found to be bioavailable in all the subjects tested, hence it can be used for supplementary feeding programmes to combat vitamin A deficiency in target population.
AuthorsR Manorama, G N Brahmam, C Rukmini
JournalPlant foods for human nutrition (Dordrecht, Netherlands) (Plant Foods Hum Nutr) Vol. 49 Issue 1 Pg. 75-82 (Jan 1996) ISSN: 0921-9668 [Print] NETHERLANDS
PMID9139306 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References
  • Plant Oils
  • Serum Albumin
  • beta Carotene
  • Vitamin A
  • palm oil
  • Child
  • Dose-Response Relationship, Drug
  • Female
  • Food, Fortified
  • Humans
  • India (epidemiology)
  • Male
  • Plant Oils (chemistry, therapeutic use)
  • Serum Albumin (analysis)
  • Time Factors
  • Vitamin A (blood)
  • Vitamin A Deficiency (blood, diet therapy, epidemiology)
  • beta Carotene (analysis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: