Abstract | OBJECTIVE: DESIGN: An uncontrolled case study. SETTING: The outpatient endocrinology clinic of a university tertiary referral center. PATIENT(S): INTERVENTION(S): MAIN OUTCOME MEASURE(S): Serum concentrations of LH, FSH, and T before and after CC therapy, as well as clinical indicators of gonadal function. RESULT(S): Barely detectable levels of LH and FSH associated with hypogonadal levels of T were restored to the normal range with CC therapy. The patient experienced improved erectile function, increased testicular size and sexual hair growth, and an improved sense of well being. CONCLUSION(S): Exercise-induced hypogonadotropic hypogonadism exists as a clinical entity among male endurance athletes, and CC may provide a safe and effective treatment option for males with debilitating hypogonadism related to endurance exercise.
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Authors | M R Burge, R A Lanzi, S T Skarda, R P Eaton |
Journal | Fertility and sterility
(Fertil Steril)
Vol. 67
Issue 4
Pg. 783-5
(Apr 1997)
ISSN: 0015-0282 [Print] United States |
PMID | 9093212
(Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Fertility Agents, Female
- Clomiphene
- Testosterone
- Estradiol
- Luteinizing Hormone
- Follicle Stimulating Hormone
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Topics |
- Adult
- Clomiphene
(administration & dosage, therapeutic use)
- Estradiol
(blood, metabolism)
- Fertility Agents, Female
(administration & dosage, therapeutic use)
- Follicle Stimulating Hormone
(blood, metabolism)
- Humans
- Hypogonadism
(blood, diagnosis, drug therapy, metabolism)
- Luteinizing Hormone
(blood, metabolism)
- Male
- Running
(physiology)
- Testosterone
(blood, metabolism)
- Time Factors
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