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Myocardial bridging in a survivor of sudden cardiac near-death: role of intracoronary doppler flow measurements and angiography during dobutamine stress in the clinical evaluation.

Abstract
Extensive myocardial bridging in the left anterior descending coronary artery was found in a 46 year old survivor of sudden cardiac near-death. Positron emission tomography and dobutamine stress echocardiography revealed ischaemia in the myocardium distal to the bridging. Spasm was excluded as cause of the ischaemia by intracoronary infusion of acetylcholine. Further evaluation of the haemodynamic importance of the bridging using intracoronary Doppler flow velocity measurements revealed an abnormal flow reserve. Dobutamine stress during coronary angiography caused increased mechanical compression during diastole. This was accompanied by multiple premature ventricular contractions. After a debridging operation the flow velocity reserve was normal. The abnormalities found during dobutamine stress had disappeared. Unexpectedly, a spasm was inducible. This may have been due to local oedema or scar formation after the operation. For the evaluation of the haemodynamic importance of myocardial bridging, intracoronary Doppler flow velocity measurements and angiography during dobutamine stress may be helpful in clinical decision making.
AuthorsR A Tio, I C Van Gelder, P W Boonstra, H J Crijns
JournalHeart (British Cardiac Society) (Heart) Vol. 77 Issue 3 Pg. 280-2 (Mar 1997) ISSN: 1355-6037 [Print] England
PMID9093051 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cardiotonic Agents
  • Dobutamine
Topics
  • Cardiotonic Agents
  • Coronary Angiography
  • Coronary Circulation
  • Coronary Vessel Anomalies (complications, surgery)
  • Dobutamine
  • Echocardiography, Doppler
  • Heart Arrest (diagnosis, etiology, surgery)
  • Humans
  • Male
  • Middle Aged

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