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Comparison of cytospat and pipelle endometrial biopsy instruments.

AbstractOBJECTIVE:
To compare two endometrial biopsy techniques, based on the quality of material obtained, cost effectiveness, and pain during the procedure.
STUDY DESIGN:
A single blind, randomized prospective study.
RESULTS:
A total of 365 women with peri/postmenopausal bleeding were randomized into two groups: 174 biopsied cytospat (C) and 191 biopsied with pipelle (P). Both procedures were then followed by either dilatation and curettage (D&C) or hysterectomy. Pain was evaluated in 379 patients, with the result being better tolerance for P vs. C (3.55 vs. 4.06, P = 0.07). With C, the sensitivity in histological evaluation was 82% for benign endometrium, 60% for endometrial hyperplasia and 60% for corpus uterine neoplasia as compared to the D&C and hysterectomy material. With P the sensitivity was 84, 71 and 60%, respectively for the three diagnoses, as compared to the D&C and hysterectomy material. Insufficient tissue for pathologic evaluation was present in 24% of C, 25% of P and 9.8% of D&C samples.
CONCLUSIONS:
Cost effectiveness for pipelle is slightly higher than for Cytospat.
AuthorsJ Antoni, E Folch, J Costa, C M Foradada, E Cayuela, N Combalia, M Rué
JournalEuropean journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 72 Issue 1 Pg. 57-61 (Mar 1997) ISSN: 0301-2115 [Print] Ireland
PMID9076423 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Topics
  • Adult
  • Biopsy (economics, instrumentation, methods)
  • Cost-Benefit Analysis
  • Dilatation and Curettage
  • Endometrium (pathology)
  • Female
  • Humans
  • Hyperplasia
  • Hysterectomy
  • Middle Aged
  • Pain
  • Prospective Studies
  • Uterine Neoplasms (pathology)

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