Abstract |
A 75-year-old man had for many years taken the commercially sold medicine PABRON-S whenever he caught a cold. He caught a cold and took the drug six days before admission. When PABRON-S was not available, he took PABRON-GOLD and experienced dyspnea the next day. A roentgenogram at another hospital revealed bilateral diffuse lung shadows. He was referred to our hospital. A thoracic CT scan showed bilateral interstitial shadows. Bronchoalveolar lavage fluid contained inflammatory cells including neutrophils and lymphocytes. Examination of a transbronchial lung biopsy specimen showed infiltration of mononuclear cells into the thick alveolar wall and interstitum. A drug lymphocyte stimulation test with PABRON-GOLD was positive. Based on these findings, we believe that this patient had drug-induced pneumonitis caused by PABRON-GOLD. He was treated with a steroid hormone and his symptoms resolved immediately, the abnormal roentgenographic shadows remained longer.
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Authors | M Nomura, M Fujimura, T Matsuda, M Kitagawa |
Journal | Nihon Kyobu Shikkan Gakkai zasshi
(Nihon Kyobu Shikkan Gakkai Zasshi)
Vol. 35
Issue 1
Pg. 72-6
(Jan 1997)
ISSN: 0301-1542 [Print] Japan |
PMID | 9071160
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Drug Combinations
- Nonprescription Drugs
- PABRON-GOLD
- Acetaminophen
- Muramidase
- Codeine
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Topics |
- Acetaminophen
(adverse effects)
- Aged
- Codeine
(adverse effects, analogs & derivatives)
- Drug Combinations
- Humans
- Male
- Muramidase
(adverse effects)
- Nonprescription Drugs
(adverse effects)
- Pneumonia
(chemically induced)
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