Prophylactic use of topical anti-infectives in ophthalmology.

Abstract

The prophylactic use of topical anti-infectives is indicated on the eye (1) prior to any surgery on the eye, by periorbital and conjunctival administration and, if required, intraoperatively as well; (2) in the form of the Credé prophylaxis against ophthalmia neonatorum; (3) with accidental pathogenic contamination of the eye; (4) to prevent conjunctivitis by intensive care surgical patients; (5) for the antiseptic irrigation of donor bulbi prior to keratoplasty, and (6) if required, to prevent ocular infection in a given epidemiological situation. The drug of first choice is polyvinylpyrrolidone-iodine at a concentration ranging from 1.5 to 5%. Another topical anti-infective is a 0.02 or 0.01% solution of polyhexanide, a promising medication, currently in the process of being approved.

• Authors: A Kramer, W Behrens-Baumann
• Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica) Vol. 211 Suppl 1 Pg. 68-76 ( 1997) ISSN: 0030-3755 [Print] Switzerland
• PMID: 9065941 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Infective Agents, Local
• Ophthalmic Solutions

Topics

• Animals
• Anti-Infective Agents, Local (therapeutic use)
• Antibiotic Prophylaxis
• Eye Infections (etiology, prevention & control)
• Humans
• Ophthalmic Solutions
• Postoperative Complications (prevention & control)
• Preoperative Care (methods)