Diabetic scleredema: a case report and biochemical analysis for glycosaminoglycans.

Abstract	We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid.
Authors	T Kobayashi, Y Yamasaki, T Watanabe
Journal	The Journal of dermatology (J Dermatol) Vol. 24 Issue 2 Pg. 100-3 (Feb 1997) ISSN: 0385-2407 [Print] England
PMID	9065704 (Publication Type: Case Reports, Journal Article)
Chemical References	Glycosaminoglycans Mucins Dermatan Sulfate Hyaluronic Acid Chondroitin Sulfates
Topics	Chondroitin Sulfates (analysis) Dermatan Sulfate (analysis) Diabetes Complications Female Fibrosis Glycosaminoglycans (analysis) Humans Hyaluronic Acid (analysis) Middle Aged Mucinoses (etiology, metabolism, pathology) Mucins (analysis) Scleredema Adultorum (etiology, metabolism, pathology) Skin (metabolism, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!