| Abstract | Azithromycin was given to 55 cases of lower respiratory tract infections in the doses of 500 mg on day 1, followed by 250 mg on days 2-5. It produced bacteriological cure in 70.8% patients and clinical cure or improvement in 69.09% of patients. 4.27% of patients had throat colonisation with new organisms, of which 9.09% needed a second antibiotic. The drug was well tolerated and minor side effects were noted. Gastrointestinal disturbances (16.36%) headache and giddiness (14.55%), rash (3.64%) were the noted side effects. Reduction of platelet count by 50% occurred in 12.29% of the cases compared to 0.2% reported earlier. But this thrombocytopenia was clinically not significant, as it did not cause any symptoms. |
| Authors | P Adhikari, B M Hegde, P Pereira, P Bhat, N Chowta, K V Ramesh, T V Venkatadri, M M Pai
(Affiliation: Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.)
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| Journal | Indian journal of medical sciences
(Indian J Med Sci)
Vol. 50
Issue 9
Pg. 313-7
(Sep 1996)
ISSN: 0019-5359 INDIA |
| PMID | 9057364
(Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
|
| Chemical References |
- Anti-Bacterial Agents
- Azithromycin
|
| Topics |
- Adolescent
- Anti-Bacterial Agents
(administration & dosage, therapeutic use)
- Azithromycin
(administration & dosage, therapeutic use)
- Evaluation Studies as Topic
- Female
- Humans
- India
- Male
- Respiratory Tract Infections
(drug therapy, microbiology)
- Treatment Outcome
|
