The effects of benfluramate on carbohydrate metabolism in obesity.

Abstract	Glucose turnover rate, glucose oxidation and lactate production from glucose were investigated in 5 obese subjects using the primed infusion technique, before and four weeks after a course on benfluramate therapy. All subjects lost weight on the drug. Mean glucose turnover rate, but not CO2 and lactate production increased after treatment. The changes in metabolism appear to reflect the combined effects of weight loss and drug action.
Authors	A C Asmal, W P Leary, W Deppe, C J Lockett
Journal	Research communications in chemical pathology and pharmacology (Res Commun Chem Pathol Pharmacol) Vol. 18 Issue 1 Pg. 95-103 (Sep 1977) ISSN: 0034-5164 [Print] United States
PMID	905637 (Publication Type: Journal Article)
Chemical References	Blood Glucose Lactates Fenfluramine benfluorex
Topics	Adult Blood Glucose (metabolism) Body Weight (drug effects) Carbohydrate Metabolism Female Fenfluramine (analogs & derivatives, pharmacology, therapeutic use) Humans Kinetics Lactates (blood) Male Obesity (drug therapy, metabolism) Oxidation-Reduction

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