Abstract |
An abnormal lipoprotein can be detected in the sera of patients suffering from intra- and extrahepatic cholestasis. The specificity of LP-X detection for the diagnosis of cholestasis in adult persons was proved by extensive investigations. The aim of this study was to examine the specificity of LP-X with regard to cholestasis in the postnatal phase of premature and newborn infants. 1056 sera of 270 newborns were tested and in 75% of these cases LP-X was found to be positive. Three hypothetical explanations are given concerning the appearance of LP-X in the sera of premature and newborn infants. The semi-quantitative determination of LP-X also represents a possibility for differential diagnosis of obstructive jaundice in the neonatal period.
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Authors | D Lachmann, G Eder |
Journal | Padiatrie und Padologie
(Padiatr Padol)
Vol. 12
Issue 4
Pg. 334-8
( 1977)
ISSN: 0030-9338 [Print] Austria |
Vernacular Title | Die Bedeutung von LP-X in den ersten Lebensmonaten. |
PMID | 904943
(Publication Type: English Abstract, Journal Article)
|
Chemical References |
- Lipoproteins
- Alkaline Phosphatase
- Bilirubin
|
Topics |
- Adult
- Age Factors
- Alkaline Phosphatase
(blood)
- Bilirubin
(blood)
- Birth Weight
- Cholestasis
(blood, enzymology)
- Humans
- Infant, Newborn
- Infant, Newborn, Diseases
(blood)
- Infant, Premature
- Infant, Premature, Diseases
(blood)
- Lipoproteins
(blood)
- Time Factors
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