[Endoscopic diagnosis and clinical experience of colonic tuberculosis].

Abstract

From February 1979 to May 1994, 18 cases of colonic tuberculosis were detected by colonscopy at Chang Gung Momorial Hospital, Linkou Medical Center. There were 10 males and 8 females, with mean age of 43.6. In ten, the diagnosis was confirmed histologically or bacteriologically in colonic biopsy material and post-operated lymph nodes. The remaining 8 patients was suspected on colonoscopy, and had good response to antituberculous therapy. The major symptoms were abdominal pain (83%), diarrhea (67%), and body weight loss (61%). Average duration from symptoms to diagnosis was 4.1 months. Chest X-ray revealed active pulmonary tuberculosis in 14 of 18 patients (78%), 4 of 14 patients were military type. The colonic tuberculosis involved in ileocecal area in 6, ileocecum and contiguous colonic regions in 7, segmental colonic involvement in 4, and pancolitis in 1 patient. Multiple ulceration and ulcerohypertrophic lesions were the major colonoscopic findings. Typical caseating granuloma were found in 5 cases (36%) from colonoscopic biopsy, the other 5 from surgical resected specimens. Antituberculous therapy produced remarkable symptomatic improvement in all patients except 2 cases complicated with intestinal obstruction necessitating laparotomy. Colonoscopy with biopsy is a useful diagnostic tool in early diagnosis and avoiding unnecessary laparotomy in colonic tuberculosis.

• Authors: C J Lin, C S Wu, P C Chen, Y C Kuo, K Y Chang, S S Wu, S Y Tung
• Journal: Changgeng yi xue za zhi (Changgeng Yi Xue Za Zhi) Vol. 19 Issue 4 Pg. 298-304 (Dec 1996) China (Republic : 1949- )
• PMID: 9041758 (Publication Type: English Abstract, Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Colonic Diseases (pathology, therapy)
• Colonoscopy
• Female
• Humans
• Male
• Middle Aged
• Prognosis
• Tuberculosis, Gastrointestinal (pathology, therapy)