| Abstract | In efficacy tests, 7 primary specific-pathogen-free piglets vaccinated with the Bordetella bronchiseptica and type D Pasteurella multocida bacterin-toxoid were challenged with B. bronchiseptica and type A P. multocida. Severe or moderate nasal turbinate atrophy was produced in the non-vaccinated pigs, whereas, only one of the 4 pigs in the vaccinated group had slight turbinate atrophy. Other immune sera against crude toxin of P. multocida type A or D were cross neutralized. The results of the present study show that the P. multocida serotype D bacterin-toxoid is effective against atrophic rhinitis caused by toxigenic P. multocida serotype A as well as toxigenic P. multocida serotype D. |
| Authors | T Sakano, M Okada, A Taneda, T Mukai, S Sato
(Affiliation: Zen-noh Institute of Animal Health, Chiba, Japan.)
|
| Journal | The Journal of veterinary medical science / the Japanese Society of Veterinary Science
(J Vet Med Sci)
Vol. 59
Issue 1
Pg. 55-7
(Jan 1997)
ISSN: 0916-7250 JAPAN |
| PMID | 9035080
(Publication Type: Journal Article)
|
| Chemical References |
- Bacterial Vaccines
- Pasteurella multocida bacterin-toxoid
|
| Topics |
- Animals
- Atrophy
- Bacterial Vaccines
(pharmacology)
- Bordetella
(immunology, isolation & purification)
- Bordetella Infections
(immunology, prevention & control, veterinary)
- Pasteurella Infections
(immunology, prevention & control, veterinary)
- Pasteurella multocida
(classification, immunology, isolation & purification)
- Rhinitis, Atrophic
(microbiology, pathology, veterinary)
- Serotyping
- Swine
- Swine Diseases
- Turbinates
(drug effects, pathology)
|
