Effect of Bordetella bronchiseptica and serotype D Pasteurella multocida bacterin-toxoid on the occurrence of atrophic rhinitis after experimental infection with B. bronchiseptica and toxigenic type AP. multocida.

Abstract

In efficacy tests, 7 primary specific-pathogen-free piglets vaccinated with the Bordetella bronchiseptica and type D Pasteurella multocida bacterin-toxoid were challenged with B. bronchiseptica and type A P. multocida. Severe or moderate nasal turbinate atrophy was produced in the non-vaccinated pigs, whereas, only one of the 4 pigs in the vaccinated group had slight turbinate atrophy. Other immune sera against crude toxin of P. multocida type A or D were cross neutralized. The results of the present study show that the P. multocida serotype D bacterin-toxoid is effective against atrophic rhinitis caused by toxigenic P. multocida serotype A as well as toxigenic P. multocida serotype D.

• Authors: T Sakano, M Okada, A Taneda, T Mukai, S Sato
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 59 Issue 1 Pg. 55-7 (Jan 1997) ISSN: 0916-7250 [Print] Japan
• PMID: 9035080 (Publication Type: Journal Article)

Chemical References

• Bacterial Vaccines
• Pasteurella multocida bacterin-toxoid

Topics

• Animals
• Atrophy
• Bacterial Vaccines (pharmacology)
• Bordetella (immunology, isolation & purification)
• Bordetella Infections (immunology, prevention & control, veterinary)
• Pasteurella Infections (immunology, prevention & control, veterinary)
• Pasteurella multocida (classification, immunology, isolation & purification)
• Rhinitis, Atrophic (microbiology, pathology, veterinary)
• Serotyping
• Swine
• Swine Diseases
• Turbinates (drug effects, pathology)