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[Paraneoplastic pemphigus in chronic lymphocytic leukemia]

AbstractINTRODUCTION: Paraneoplastic pemphigus is an autoimmune bullous disease described by precise clinical, histological and immunological features presented by Anhalt in 1990. Prognosis is very severe and depends on the associated neoplasia and the gravity of the mucosal damage. CASE REPORT: Paraneoplastic pemphigus was diagnosed in a 62-year-old man with chronic lymphoid leukemia. The course was favorable up to one-year follow-up after general corticosteroid therapy. DISCUSSION: This case illustrates that paraneoplastic pemphigus can be controlled by general corticosteroids and would suggest the severe prognosis may be improved.
AuthorsB Fournier, F Bouscarat, P Le Bozec, P Joly, P Gardin, M Grossin, V Descamps, B Crickx, S Belaïch (Affiliation: Service de Dermatologie, Hôpital Bichat, Paris.)
JournalAnnales de dermatologie et de vénéréologie (Ann Dermatol Venereol) Vol. 123 Issue 8 Pg. 483-6 ( 1996) ISSN: 0151-9638 FRANCE
Vernacular TitlePemphigus paranéoplasique au cours d'une leucémie lymphoïde chronique.
PMID9033721 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Glucocorticoids
  • Prednisone
Topics
  • Glucocorticoids (therapeutic use)
  • Humans
  • Immunohistochemistry
  • Leukemia, Lymphocytic, Chronic, B-Cell (complications)
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes
  • Pemphigus (drug therapy, etiology, pathology)
  • Prednisone (therapeutic use)