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Two cases of Merkel cell carcinoma cured by intratumor injection of natural human tumor necrosis factor.

Abstract
Two patients were treated with intratumor injection of natural human tumor necrosis factor for recurrent or primary Merkel cell carcinoma. In both patients, local chemotherapy achieved complete tumor regression without causing ulceration or scarring. These results suggest that intratumor injection of natural human tumor necrosis factor may be very effective for the treatment of Merkel cell carcinoma.
AuthorsY Hata, K Matsuka, O Ito, H Matsuda, H Furuichi, A Konstantinos, B Nuri
JournalPlastic and reconstructive surgery (Plast Reconstr Surg) Vol. 99 Issue 2 Pg. 547-53 (Feb 1997) ISSN: 0032-1052 [Print] United States
PMID9030166 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Tumor Necrosis Factor-alpha
Topics
  • Aged
  • Carcinoma, Merkel Cell (therapy)
  • Female
  • Humans
  • Injections, Intralesional
  • Remission Induction
  • Skin Neoplasms (therapy)
  • Tumor Necrosis Factor-alpha (administration & dosage)

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