Phenobarbital-induced gingival overgrowth? Report of two cases and complications in management.

Abstract	Gingival overgrowth is a known side effect of several seizure, immunosuppressant and calcium channel-blocker medications. Gingival overgrowth is not a reported side-effect of phenobarbital. This case report describes two patients with marked gingival overgrowth who had been medicated with phenobarbital exclusively since the initiation of seizure disorders. The clinical findings, surgical management, bleeding complications, and recommendations in management are discussed.
Authors	A P Gregoriou, P E Schneider, P R Shaw
Journal	ASDC journal of dentistry for children (ASDC J Dent Child) 1996 Nov-Dec Vol. 63 Issue 6 Pg. 408-13 ISSN: 1945-1954 [Print] United States
PMID	9017173 (Publication Type: Case Reports, Journal Article)
Chemical References	Anticonvulsants Hemostatics Thrombin Phenobarbital
Topics	Adolescent Anticonvulsants (adverse effects) Blood Transfusion Gingival Overgrowth (chemically induced, surgery) Gingivectomy (adverse effects) Hemostatics (therapeutic use) Humans Male Phenobarbital (adverse effects) Postoperative Hemorrhage (etiology, therapy) Thrombin (therapeutic use)

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