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[Immunophenotypic characterization of cutaneous neuroendocrine carcinoma derived from Merkel cells].

Abstract
The following immunohistochemical markers were studied in 5 Merkel cell carcinomas: cytokeratins, epithelial membrane component, neuron-specific enolase, synaptophysin and chromogranin A. High expression of these markers in tumors allows one to consider them as having epithelial origin with neuroendocrine differentiation. Common leucocytic antigen proved to be very useful in differential diagnosis with malignant lymphoma.
AuthorsK M Pozharisskiĭ, A Iu Ivanova, E E Leenman, N A Abroian
JournalArkhiv patologii (Arkh Patol) 1996 Sep-Oct Vol. 58 Issue 5 Pg. 13-8 ISSN: 0004-1955 [Print] Russia (Federation)
Vernacular TitleImmunofenotipicheskaia kharakteristika neĭroéndokrinnogo raka kozhi iz kletok Merkelia.
PMID9005817 (Publication Type: Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Biomarkers
Topics
  • Adult
  • Aged
  • Biomarkers (chemistry)
  • Carcinoma, Merkel Cell (chemistry, pathology)
  • Cell Differentiation (physiology)
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Immunophenotyping
  • Male
  • Middle Aged
  • Skin Neoplasms (chemistry, pathology)

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