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Guillain-Barré syndrome and cytomegalovirus infection during pregnancy.

Abstract
We report a case of Guillain-Barré syndrome and associated cytomegalovirus infection during pregnancy. A 15-year-old black adolescent had progressive ascending paralysis and vague sensory symptoms during week 10 of her first pregnancy. Diagnosis of Guillain-Barré syndrome was confirmed by electrophysiologic findings consistent with acute demyelinating polyradiculoneuropathy. A mild elevation of anti-GM1 antibodies was also detected. The patient improved with plasmapheresis treatment; however, fetal death occurred 10 weeks later. Cytomegalovirus placentitis was confirmed histologically. Acute demyelinating polyneuropathy during pregnancy warrants consideration of a concomitant, primary maternal and fetal cytomegalovirus infection.
AuthorsJ E Mendizabal, B A Bassam
JournalSouthern medical journal (South Med J) Vol. 90 Issue 1 Pg. 63-4 (Jan 1997) ISSN: 0038-4348 [Print] United States
PMID9003827 (Publication Type: Case Reports, Journal Article)
Topics
  • Adolescent
  • Cytomegalovirus Infections (diagnosis, therapy)
  • Female
  • Fetal Death
  • Humans
  • Placenta (pathology)
  • Plasmapheresis
  • Polyradiculoneuropathy (diagnosis, therapy)
  • Pregnancy
  • Pregnancy Complications, Infectious (diagnosis, therapy)

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