Abstract | BACKGROUND: The demographic and subsequent economic pressures in developing nations have contributed to the increasing levels of antibiotic resistance among both commensal flora and pathogenic bacteria. As empirical options are diminishing daily, the role of ciprofloxacin in pediatric infections is becoming increasingly significant. OBJECTIVE: RESULTS: The efficacy and safety of ciprofloxacin in children were found to be similar to those observed in adults for gastrointestinal infectious diseases. Overall the data presented confirm that ciprofloxacin is a safe and efficacious agent for use in children in the developing world. CONCLUSION:
Ciprofloxacin has been shown to be safe and efficacious in children in developing countries. Subsequently a priority for both the pharmaceutical industry and regulatory authorities in developing nations is to prevent fluoroquinolone misuse and development of antibiotic resistance.
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Authors | S Green, G Tillotson |
Journal | The Pediatric infectious disease journal
(Pediatr Infect Dis J)
Vol. 16
Issue 1
Pg. 150-9; discussion 160-2
(Jan 1997)
ISSN: 0891-3668 [Print] United States |
PMID | 9002127
(Publication Type: Journal Article)
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Chemical References |
- Anti-Infective Agents
- Ciprofloxacin
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Topics |
- Anti-Infective Agents
(therapeutic use)
- Bacterial Infections
(drug therapy)
- Child
- Ciprofloxacin
(therapeutic use)
- Developing Countries
- Digestive System
(microbiology)
- Drug Resistance, Microbial
- Drug Utilization
- Gastrointestinal Diseases
(drug therapy)
- Humans
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