Abstract | HYPOTHESIS: To create a phlebolymphologic therapy in order: to activate venous system; to activate lymphatic system; to activate macrophagic system; to reduce the proteic lymphatic load. EXPERIMENTAL: A study was performed on the use of an ideal phlebolymphological association (Tonka Beans, Gingko Biloba, Melilotus Officinalis) as a practical standpoint in the treatment of lymphedema of lower limbs in order to create an efficacious dose of Coumarin, Benzopyrones and Ginkolidi. CLINICAL: We investigated a population of 76 patients treated in an open-label study for six-eight months with a dosage of Coumarin 60 mg/daily + Gingko Biloba 40 mg/daily + Melilotus 40 mg/daily. CONCLUSION: This trilogy induced a very significant improvement in lymphedema (centimeter-aspect) both in functional symptoms ( pain heaviness in affected limbs) and physical signs ( edema, episodes of infection). Tolerance of long term treatment was good and the improvement was observed from the third month of treatment.
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Authors | G Vettorello, G Cerreta, A Derwish, A Cataldi, A Schettino, S Occhionorelli, I Donini |
Journal | Minerva cardioangiologica
(Minerva Cardioangiol)
Vol. 44
Issue 9
Pg. 447-55
(Sep 1996)
ISSN: 0026-4725 [Print] Italy |
Vernacular Title | Contributo di un'associazione di alpha e beta benzopironi, flavonoidi e terpeni di derivazione naturale, nel trattamento del linfedema degli arti inferiori al II stadio della classificazione operativa. |
PMID | 8999369
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
- Anticoagulants
- Coumarins
- Plant Extracts
- coumarin
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Topics |
- Adolescent
- Adult
- Aged
- Anticoagulants
(administration & dosage)
- Coumarins
(administration & dosage)
- Drainage
- Drug Therapy, Combination
- Follow-Up Studies
- Humans
- Leg
- Lymphedema
(classification, drug therapy, surgery)
- Middle Aged
- Phytotherapy
- Plant Extracts
(administration & dosage)
- Time Factors
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