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[Duodenal ulcer: clinical significance of adaptation defects in the system of neurohumoral regulation].

Abstract
Radioimmunoassay was used to determine prostaglandin (PGE-2) and cyclic nucleotides (cAMP and cGMP) concentrations in the serum before, 1 and 2 hours after standard test breakfast (5066 kJ) in 65 patients with duodenal ulcer. Basal hyperproduction of prostaglandins and cyclic nucleotides were interpreted as an adaptation-compensatory mechanism. The unbalance of their aftermeal reactions persistent even in ulcer healing may belong to factors of the disease progression.
AuthorsE I Eremina
JournalKlinicheskaia meditsina (Klin Med (Mosk)) Vol. 74 Issue 4 Pg. 29-31 ( 1996) ISSN: 0023-2149 [Print] Russia (Federation)
Vernacular TitleIazvennaia bolezn' dvenadtsatiperstnoi kishki: klinicheskoe znachenie dezaptatsionnykh rasstroistv v sisteme neirogumoral'noi reguliatsii.
PMID8999147 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Dinoprost
  • Cyclic AMP
  • Cyclic GMP
  • Dinoprostone
Topics
  • Adaptation, Biological
  • Adult
  • Biopsy
  • Cyclic AMP (blood)
  • Cyclic GMP (blood)
  • Dinoprost (blood)
  • Dinoprostone (blood)
  • Duodenal Ulcer (blood, pathology)
  • Endoscopy, Digestive System
  • Humans
  • Male
  • Middle Aged
  • Radioimmunoassay

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