Abstract |
Sulthiame is effectively used in the treatment of benign and symptomatic focal epilepsy in children. Hyperventilation as a symptom is a well known adverse effect of the drug. Alterations of the acid-base equilibrium have been described for the drug, however, very infrequently only in adults without a detailed evaluation of the disorders status. The case presented here demonstrates a mild compensated metabolic acidosis in a child which, for the first time, is described using the methods of complete blood gas and electrolytes analysis.
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Authors | U Tröger, C Fritzsch, J Darius, J Gedschold, F P Meyer |
Journal | International journal of clinical pharmacology and therapeutics
(Int J Clin Pharmacol Ther)
Vol. 34
Issue 12
Pg. 542-5
(Dec 1996)
ISSN: 0946-1965 [Print] Germany |
PMID | 8996849
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anticonvulsants
- Thiazines
- sulthiame
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Topics |
- Acidosis
(blood, chemically induced)
- Anticonvulsants
(adverse effects)
- Blood Gas Analysis
- Child, Preschool
- Epilepsy
(blood, drug therapy)
- Humans
- Male
- Thiazines
(adverse effects)
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