[Possible prediction of the preventive use of lithium in affective psychoses based on a study of the erythrocyte index].

Abstract

In 70 patients with affective psychosis, who were prophylactically treated by lithium carbonate (the mean duration of treatment was 1692 days) the authors studied the erythrocyte index (the ratio of lithium content in the erythrocytes to its content in the serum). It was found that the highest index was in the depressive phase and the lowest one in remissions. The success of prophylactic treatment during remissions positively correlated with the increase of the erythrocyte index. The lithium index is of interest only with consideration of the phase of the disease.

• Authors: Ia Shvestka, K Nagunek
• Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 77 Issue 8 Pg. 1227-9 ( 1977) ISSN: 0044-4588 [Print] Russia (Federation)
• Vernacular Title: O vozmozhnosti predskazaniia rezul'tatov profilakticheskogo ispol'zovaniia litiia pri affektivnykh psikhozakh na osnove izucheniia ego éritrotsitarnogo indekesa.
• PMID: 899538 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lithium

Topics

• Adult
• Aged
• Bipolar Disorder (blood, drug therapy)
• Erythrocytes (analysis)
• Humans
• Lithium (blood, therapeutic use)
• Middle Aged
• Prognosis