Abstract |
Neutralizing antibodies are a major component of host defense against viruses, and appear to be particularly important in limiting the spread of cell-free virus. Results from vaccine trials in animal models suggest that these antibodies may contribute to protection against human immunodeficiency virus ( HIV) infection. Here, Pascal Poignard and colleagues discuss recent developments in this area, with particular emphasis on the measurement, specificity and mechanism of the antibody response, and its significance for vaccine production.
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Authors | P Poignard, P J Klasse, Q J Sattentau |
Journal | Immunology today
(Immunol Today)
Vol. 17
Issue 5
Pg. 239-46
(May 1996)
ISSN: 0167-5699 [Print] England |
PMID | 8991386
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Amino Acid Sequence
- HIV Antibodies
(pharmacology)
- HIV-1
(immunology)
- Humans
- Molecular Sequence Data
- Neutralization Tests
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