Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease.

Abstract

UNLABELLED:

We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.

CONCLUSION:

Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.

• Authors: T A De Heer-Groen, A B Prakken, N M Bax, P J van Dijken
• Journal: European journal of pediatrics (Eur J Pediatr) Vol. 155 Issue 12 Pg. 1015-7 (Dec 1996) ISSN: 0340-6199 [Print] Germany
• PMID: 8956935 (Publication Type: Case Reports, Journal Article)

Chemical References

• Iron

Topics

• Adolescent
• Anemia (drug therapy, etiology)
• Castleman Disease (diagnosis, physiopathology, surgery)
• Female
• Humans
• Iron (therapeutic use)